Fibronectin matrix formation and signaling via integrins on biomaterials

G. Altankov, F. Grinnell, Th Groth

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The surface wettability of biomaterials affect the ability of cells to reorganize preadsorbed fibronectin (FN) and to form their own matrix by secreted FN. Moderate wettable and hydrophilic surfaces are ideal for better interactions with cells while hydrophobic substrata inhibit early and late matrix formation. It is possible that there is a critical value in the strength of FN adsorption which regulates the ability of cells to construct a FN matrix.

Original languageEnglish (US)
Title of host publicationTransactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium
Editors Anon
Place of PublicationSt. Louis Park, MN, United States
PublisherSoc for Biomaterials
Pages281
Number of pages1
Volume1
StatePublished - 1996
EventProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) - Toronto, Can
Duration: May 29 1996Jun 2 1996

Other

OtherProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2)
CityToronto, Can
Period5/29/966/2/96

ASJC Scopus subject areas

  • Materials Science(all)

Fingerprint Dive into the research topics of 'Fibronectin matrix formation and signaling via integrins on biomaterials'. Together they form a unique fingerprint.

  • Cite this

    Altankov, G., Grinnell, F., & Groth, T. (1996). Fibronectin matrix formation and signaling via integrins on biomaterials. In Anon (Ed.), Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium (Vol. 1, pp. 281). Soc for Biomaterials.