Finite element analysis of mitral valve pathology

K. S. Kunzelman, R. P. Cochran, E. D. Verrier, C. J. Chuong, W. S. Ring, R. C. Eberhart

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26 Scopus citations

Abstract

A finite element model was developed to examine deformation and stress patterns in the pathologic mitral valve under systolic loading conditions. A nonlinear, transient, equilibrium analysis was utilized to include time-dependent loading and chordal element bilinearity. Simulated conditions included chordal rupture, annular dilatation, and leaflet perforation. Chordal rupture produced leaflet prolapse, and increased stress on the remaining chordae. Annular dilatation resulted in delayed valve closure and significantly increased stress throughout the valve. Leaflet perforation demonstrated stress concentrations, which may lead to further tearing. Each of these models gives insight into possible mechanisms of valve failure.

Original languageEnglish (US)
Pages (from-to)161-179
Number of pages19
JournalJournal of Long-Term Effects of Medical Implants
Volume3
Issue number3
Publication statusPublished - 1993

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ASJC Scopus subject areas

  • Biomedical Engineering
  • Medicine (miscellaneous)
  • Orthopedics and Sports Medicine
  • Pathology and Forensic Medicine

Cite this

Kunzelman, K. S., Cochran, R. P., Verrier, E. D., Chuong, C. J., Ring, W. S., & Eberhart, R. C. (1993). Finite element analysis of mitral valve pathology. Journal of Long-Term Effects of Medical Implants, 3(3), 161-179.