Finite element analysis of the mitral valve.

K. S. Kunzelman, R. P. Cochran, C. Chuong, W. S. Ring, E. D. Verrier, R. D. Eberhart

Research output: Contribution to journalArticle

167 Citations (Scopus)

Abstract

A finite element model was developed to examine deformation and stress patterns in the mitral valve under systolic loading conditions. This is the first three-dimensional finite element model of the mitral valve, incorporating all essential anatomic components, regional tissue thickness, collagen fiber orientation and related anisotropic material properties. A non-linear, transient, dynamic analysis was performed which included time-dependent loading, leaflet and chordal mass inertial effects and chordal element bi-linearity. The model was first analyzed without either annular or papillary muscle contraction and then with either or both. The hypothesis was that the combination of annular and papillary muscle contraction would have a beneficial effect on valve function. In all models, the computed anterior leaflet principal stresses were tensile and of greater magnitude than those in the posterior leaflet. The principal stress directions were observed to correlate well with collagen fiber orientation. Earlier leaflet coaptation was demonstrated with annular contraction, promoting valve closure, while papillary muscle contraction increased the stress on the chordae tendineae and both leaflets, tending to pull the latter apart. The combination of the two combined these effects, and showed the most even stress distribution. The effects of annular and papillary muscle contraction on valve function were shown to be beneficial by this model, and they can be further elucidated by varying the extent and timing of the individual contractions. This model can be used to examine the effects of pathologic changes, surgical manipulations and proposed material replacements. It can thus aid both the surgeon and the biomedical engineer in improving the materials and techniques available for the repair and/or replacement of mitral valve system components.

Original languageEnglish (US)
Pages (from-to)326-340
Number of pages15
JournalThe Journal of heart valve disease
Volume2
Issue number3
StatePublished - May 1993

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Finite Element Analysis
Papillary Muscles
Muscle Contraction
Mitral Valve
Collagen
Chordae Tendineae
Nonlinear Dynamics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Kunzelman, K. S., Cochran, R. P., Chuong, C., Ring, W. S., Verrier, E. D., & Eberhart, R. D. (1993). Finite element analysis of the mitral valve. The Journal of heart valve disease, 2(3), 326-340.

Finite element analysis of the mitral valve. / Kunzelman, K. S.; Cochran, R. P.; Chuong, C.; Ring, W. S.; Verrier, E. D.; Eberhart, R. D.

In: The Journal of heart valve disease, Vol. 2, No. 3, 05.1993, p. 326-340.

Research output: Contribution to journalArticle

Kunzelman, KS, Cochran, RP, Chuong, C, Ring, WS, Verrier, ED & Eberhart, RD 1993, 'Finite element analysis of the mitral valve.', The Journal of heart valve disease, vol. 2, no. 3, pp. 326-340.
Kunzelman KS, Cochran RP, Chuong C, Ring WS, Verrier ED, Eberhart RD. Finite element analysis of the mitral valve. The Journal of heart valve disease. 1993 May;2(3):326-340.
Kunzelman, K. S. ; Cochran, R. P. ; Chuong, C. ; Ring, W. S. ; Verrier, E. D. ; Eberhart, R. D. / Finite element analysis of the mitral valve. In: The Journal of heart valve disease. 1993 ; Vol. 2, No. 3. pp. 326-340.
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