Finite element simulation of cooling of realistic 3-D human head and neck

Brian H. Dennis, Robert C. Eberhart, George S. Dulikravich, Steve W. Radons

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Rapid cooling of the brain in the first minutes following the onset of cerebral ischemia is a potentially attractive preservation method. This computer modeling study was undertaken to examine brain-cooling profiles in response to various external cooling methods and protocols, in order to guide the development of clinical cooling devices. The criterion of successful cooling is the attainment of a 33.0 °C average brain temperature within 30 minutes of treatment. Comparison of the finite element model results with a formal mathematical solution, give confidence that the simulation methods are sound. The cooling simulations considered to date all indicate that no one means of external cooling of the head or neck is sufficient to cool the brain in a reasonable period of time (30 minutes). Neither ice packs applied to head or neck, or cooling helmets can satisfy the 33.0 °C target temperature specification. This central conclusion of insubstantial cooling is supported by the modest enhancements reported in experimental investigations of externally applied cooling. The key problem is overcoming the protective effect of warm blood perfusion, which reaches the brain via the uncooled carotid arterial supply and effectively blocks the external cooling wave from advancing to the core of the brain. This suggests that other cooling means should be explored requiring a realistic simulation of cooling of other pertinent parts of the human anatomy.

Original languageEnglish (US)
Title of host publicationAmerican Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD
EditorsY. Bayazitoglu, J. Bischof, L. Xu, E. Scott
Pages69-81
Number of pages13
Volume373
DOIs
StatePublished - 2002
Event2002 ASME International Mechanical Engineering Congress and Exposition - New orleans, LA, United States
Duration: Nov 17 2002Nov 22 2002

Other

Other2002 ASME International Mechanical Engineering Congress and Exposition
CountryUnited States
CityNew orleans, LA
Period11/17/0211/22/02

Fingerprint

Cooling
Brain
Ice
Blood
Acoustic waves
Specifications
Temperature

ASJC Scopus subject areas

  • Mechanical Engineering
  • Fluid Flow and Transfer Processes

Cite this

Dennis, B. H., Eberhart, R. C., Dulikravich, G. S., & Radons, S. W. (2002). Finite element simulation of cooling of realistic 3-D human head and neck. In Y. Bayazitoglu, J. Bischof, L. Xu, & E. Scott (Eds.), American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD (Vol. 373, pp. 69-81) https://doi.org/10.1115/IMECE2002-32045

Finite element simulation of cooling of realistic 3-D human head and neck. / Dennis, Brian H.; Eberhart, Robert C.; Dulikravich, George S.; Radons, Steve W.

American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD. ed. / Y. Bayazitoglu; J. Bischof; L. Xu; E. Scott. Vol. 373 2002. p. 69-81.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Dennis, BH, Eberhart, RC, Dulikravich, GS & Radons, SW 2002, Finite element simulation of cooling of realistic 3-D human head and neck. in Y Bayazitoglu, J Bischof, L Xu & E Scott (eds), American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD. vol. 373, pp. 69-81, 2002 ASME International Mechanical Engineering Congress and Exposition, New orleans, LA, United States, 11/17/02. https://doi.org/10.1115/IMECE2002-32045
Dennis BH, Eberhart RC, Dulikravich GS, Radons SW. Finite element simulation of cooling of realistic 3-D human head and neck. In Bayazitoglu Y, Bischof J, Xu L, Scott E, editors, American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD. Vol. 373. 2002. p. 69-81 https://doi.org/10.1115/IMECE2002-32045
Dennis, Brian H. ; Eberhart, Robert C. ; Dulikravich, George S. ; Radons, Steve W. / Finite element simulation of cooling of realistic 3-D human head and neck. American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD. editor / Y. Bayazitoglu ; J. Bischof ; L. Xu ; E. Scott. Vol. 373 2002. pp. 69-81
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