Abstract
Purpose: UsingMicroPerimetryMP-1 to assess the fixation behavior in early and moderate primary open angle glaucoma (POAG). Methods: Thirty-nine early and moderate POAG eyes and 22 normal eyes were enrolled prospectively. The stability and location of the fixation in each subject eye were recorded by the macula 10-degree program of the microperimeter (MP-1). Retinal sensitivity was examined using the G2 program phase 1 of an Octopus 101 perimeter and the macula 10-degree program of the MP-1. The fixation behavior and the retinal sensitivity were compared between POAG and control groups. The correlation between the fixation behavior and the retinal sensitivity was analyzed in POAG patients. Results: Fixation instability was detected in POAG (P=0.016). It correlated with the mean defect on Octopus perimeter and all the mean macular sensitivity parameters of MP-1, which includes the central 10 degrees (r=0.416, P=0.008), 6 degrees (r=0.401, P= 0.011), 2 degrees (r=0.376, P=0.018), inferotemporal (r=0.399, P=0.012) and inferonasal (r=0.387, P=0.015) quadrants of the central 6 degrees. All the POAG patients had a predominantly central fixation. Conclusion: Fixation instability manifested in early and moderate POAG eyes, which may be an early sign of POAG.
Original language | English (US) |
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Pages (from-to) | 169-173 |
Number of pages | 5 |
Journal | Journal of Glaucoma |
Volume | 22 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2013 |
Keywords
- Fixation behavior
- Microperimetry
- Primary open angle glaucoma
- Retinal sensitivity
ASJC Scopus subject areas
- Ophthalmology