Fixation behavior in primary open angle glaucoma at early and moderate stage assessed by the microperimeter MP-1

Yan Shi, Mugen Liu, Xin Wang, Chun Zhang, Ping Huang

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Purpose: UsingMicroPerimetryMP-1 to assess the fixation behavior in early and moderate primary open angle glaucoma (POAG). Methods: Thirty-nine early and moderate POAG eyes and 22 normal eyes were enrolled prospectively. The stability and location of the fixation in each subject eye were recorded by the macula 10-degree program of the microperimeter (MP-1). Retinal sensitivity was examined using the G2 program phase 1 of an Octopus 101 perimeter and the macula 10-degree program of the MP-1. The fixation behavior and the retinal sensitivity were compared between POAG and control groups. The correlation between the fixation behavior and the retinal sensitivity was analyzed in POAG patients. Results: Fixation instability was detected in POAG (P=0.016). It correlated with the mean defect on Octopus perimeter and all the mean macular sensitivity parameters of MP-1, which includes the central 10 degrees (r=0.416, P=0.008), 6 degrees (r=0.401, P= 0.011), 2 degrees (r=0.376, P=0.018), inferotemporal (r=0.399, P=0.012) and inferonasal (r=0.387, P=0.015) quadrants of the central 6 degrees. All the POAG patients had a predominantly central fixation. Conclusion: Fixation instability manifested in early and moderate POAG eyes, which may be an early sign of POAG.

Original languageEnglish (US)
Pages (from-to)169-173
Number of pages5
JournalJournal of Glaucoma
Volume22
Issue number2
DOIs
StatePublished - Feb 1 2013

Keywords

  • Fixation behavior
  • Microperimetry
  • Primary open angle glaucoma
  • Retinal sensitivity

ASJC Scopus subject areas

  • Ophthalmology

Fingerprint Dive into the research topics of 'Fixation behavior in primary open angle glaucoma at early and moderate stage assessed by the microperimeter MP-1'. Together they form a unique fingerprint.

  • Cite this