Functional magnetic resonance imaging of human auditory cortex

J. R. Binder, S. M. Rao, T. A. Hammeke, F. Z. Yetkin, A. Jesmanowicz, P. A. Bandettini, E. C. Wong, L. D. Estkowski, M. D. Goldstein, V. M. Haughton, J. S. Hyde

Research output: Contribution to journalArticle

329 Citations (Scopus)

Abstract

Magnetic resonance imaging methods recently demonstrated regional cerebral signal changes in response to limb movement and visual stimulation, attributed to blood flow enhancement. We studied 5 normal subjects scanned while listening to auditory stimuli including nonspeech noise, meaningless speech sounds, single words, and narrative text. Imaged regions included the lateral aspects of both hemispheres. Signal changes in the superior temporal gyrus and superior temporal sulcus were observed bilaterally in all subjects. Speech stimuli were associated with significantly more widespread signal changes than was the noise stimulus, while no consistent differences were observed between responses to different speech stimuli. Considerable intersubject variability in the topography of signal changes was observed. These observations confirm the utility of magnetic resonance imaging in the study of human brain structure-function relationships and emphasize the role of the superior temporal gyrus in perception of acoustic-phonetic features of speech, rather than processing of semantic features.

Original languageEnglish (US)
Pages (from-to)662-672
Number of pages11
JournalAnnals of Neurology
Volume35
Issue number6
DOIs
StatePublished - Jun 1994

Fingerprint

Auditory Cortex
Temporal Lobe
Phonetics
Magnetic Resonance Imaging
Noise
Photic Stimulation
Semantics
Acoustics
Extremities
Brain

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Binder, J. R., Rao, S. M., Hammeke, T. A., Yetkin, F. Z., Jesmanowicz, A., Bandettini, P. A., ... Hyde, J. S. (1994). Functional magnetic resonance imaging of human auditory cortex. Annals of Neurology, 35(6), 662-672. https://doi.org/10.1002/ana.410350606

Functional magnetic resonance imaging of human auditory cortex. / Binder, J. R.; Rao, S. M.; Hammeke, T. A.; Yetkin, F. Z.; Jesmanowicz, A.; Bandettini, P. A.; Wong, E. C.; Estkowski, L. D.; Goldstein, M. D.; Haughton, V. M.; Hyde, J. S.

In: Annals of Neurology, Vol. 35, No. 6, 06.1994, p. 662-672.

Research output: Contribution to journalArticle

Binder, JR, Rao, SM, Hammeke, TA, Yetkin, FZ, Jesmanowicz, A, Bandettini, PA, Wong, EC, Estkowski, LD, Goldstein, MD, Haughton, VM & Hyde, JS 1994, 'Functional magnetic resonance imaging of human auditory cortex', Annals of Neurology, vol. 35, no. 6, pp. 662-672. https://doi.org/10.1002/ana.410350606
Binder JR, Rao SM, Hammeke TA, Yetkin FZ, Jesmanowicz A, Bandettini PA et al. Functional magnetic resonance imaging of human auditory cortex. Annals of Neurology. 1994 Jun;35(6):662-672. https://doi.org/10.1002/ana.410350606
Binder, J. R. ; Rao, S. M. ; Hammeke, T. A. ; Yetkin, F. Z. ; Jesmanowicz, A. ; Bandettini, P. A. ; Wong, E. C. ; Estkowski, L. D. ; Goldstein, M. D. ; Haughton, V. M. ; Hyde, J. S. / Functional magnetic resonance imaging of human auditory cortex. In: Annals of Neurology. 1994 ; Vol. 35, No. 6. pp. 662-672.
@article{054e2c67383b4239a4791ee451b28730,
title = "Functional magnetic resonance imaging of human auditory cortex",
abstract = "Magnetic resonance imaging methods recently demonstrated regional cerebral signal changes in response to limb movement and visual stimulation, attributed to blood flow enhancement. We studied 5 normal subjects scanned while listening to auditory stimuli including nonspeech noise, meaningless speech sounds, single words, and narrative text. Imaged regions included the lateral aspects of both hemispheres. Signal changes in the superior temporal gyrus and superior temporal sulcus were observed bilaterally in all subjects. Speech stimuli were associated with significantly more widespread signal changes than was the noise stimulus, while no consistent differences were observed between responses to different speech stimuli. Considerable intersubject variability in the topography of signal changes was observed. These observations confirm the utility of magnetic resonance imaging in the study of human brain structure-function relationships and emphasize the role of the superior temporal gyrus in perception of acoustic-phonetic features of speech, rather than processing of semantic features.",
author = "Binder, {J. R.} and Rao, {S. M.} and Hammeke, {T. A.} and Yetkin, {F. Z.} and A. Jesmanowicz and Bandettini, {P. A.} and Wong, {E. C.} and Estkowski, {L. D.} and Goldstein, {M. D.} and Haughton, {V. M.} and Hyde, {J. S.}",
year = "1994",
month = "6",
doi = "10.1002/ana.410350606",
language = "English (US)",
volume = "35",
pages = "662--672",
journal = "Annals of Neurology",
issn = "0364-5134",
publisher = "John Wiley and Sons Inc.",
number = "6",

}

TY - JOUR

T1 - Functional magnetic resonance imaging of human auditory cortex

AU - Binder, J. R.

AU - Rao, S. M.

AU - Hammeke, T. A.

AU - Yetkin, F. Z.

AU - Jesmanowicz, A.

AU - Bandettini, P. A.

AU - Wong, E. C.

AU - Estkowski, L. D.

AU - Goldstein, M. D.

AU - Haughton, V. M.

AU - Hyde, J. S.

PY - 1994/6

Y1 - 1994/6

N2 - Magnetic resonance imaging methods recently demonstrated regional cerebral signal changes in response to limb movement and visual stimulation, attributed to blood flow enhancement. We studied 5 normal subjects scanned while listening to auditory stimuli including nonspeech noise, meaningless speech sounds, single words, and narrative text. Imaged regions included the lateral aspects of both hemispheres. Signal changes in the superior temporal gyrus and superior temporal sulcus were observed bilaterally in all subjects. Speech stimuli were associated with significantly more widespread signal changes than was the noise stimulus, while no consistent differences were observed between responses to different speech stimuli. Considerable intersubject variability in the topography of signal changes was observed. These observations confirm the utility of magnetic resonance imaging in the study of human brain structure-function relationships and emphasize the role of the superior temporal gyrus in perception of acoustic-phonetic features of speech, rather than processing of semantic features.

AB - Magnetic resonance imaging methods recently demonstrated regional cerebral signal changes in response to limb movement and visual stimulation, attributed to blood flow enhancement. We studied 5 normal subjects scanned while listening to auditory stimuli including nonspeech noise, meaningless speech sounds, single words, and narrative text. Imaged regions included the lateral aspects of both hemispheres. Signal changes in the superior temporal gyrus and superior temporal sulcus were observed bilaterally in all subjects. Speech stimuli were associated with significantly more widespread signal changes than was the noise stimulus, while no consistent differences were observed between responses to different speech stimuli. Considerable intersubject variability in the topography of signal changes was observed. These observations confirm the utility of magnetic resonance imaging in the study of human brain structure-function relationships and emphasize the role of the superior temporal gyrus in perception of acoustic-phonetic features of speech, rather than processing of semantic features.

UR - http://www.scopus.com/inward/record.url?scp=0028358402&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028358402&partnerID=8YFLogxK

U2 - 10.1002/ana.410350606

DO - 10.1002/ana.410350606

M3 - Article

C2 - 8210222

AN - SCOPUS:0028358402

VL - 35

SP - 662

EP - 672

JO - Annals of Neurology

JF - Annals of Neurology

SN - 0364-5134

IS - 6

ER -