Functional MRI-guided surgery of intracranial tumors

Michael Schulder, Joseph A Maldjian, Wen Ching Liu, In Ki Mun, Peter W. Carmel

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

We describe a technique of registering functional magnetic resonance image (fMRI) data sets with the anatomical images used for intraoperative navigation. Three patients with supratentorial tumors were studied, 2 with astrocytomas and 1 with a meningioma. The day before surgery, a functional blood-oxygen-level-dependent MR scan was done. During the same imaging session, an anatomic stereotactic MR scan was performed. The raw data were reconstructed off line on a workstation, and the fMR maps were then registered to the anatomic studies using image header information. Fused images were then transferred to the navigational workstation over an Ethernet connection. At surgery, brain exposure was performed in a standard manner. In each case, the registered scans accurately localized the motor and/or sensory cortex. No new permanent neurological deficits resulted from surgery. The potential advantages of fMRI-guided surgery include: (1) smaller brain exposures; (2) localization of language cortex under general anesthesia; (3) mapping of multiple functional sites, with decreased time and increased ease of surgery.

Original languageEnglish (US)
Pages (from-to)98-105
Number of pages8
JournalStereotactic and Functional Neurosurgery
Volume68
Issue number1-4
DOIs
StatePublished - Dec 1 1997

Fingerprint

Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Supratentorial Neoplasms
Computer-Assisted Surgery
Neoplasms
Astrocytoma
Brain
Meningioma
Ambulatory Surgical Procedures
General Anesthesia
Language
Oxygen
Datasets
Sensorimotor Cortex

Keywords

  • Brain mapping
  • Brain neoplasm
  • Functional magnetic resonance imaging (fMRI)
  • Image-guided neurosurgery
  • Stereotactic neurosurgery
  • Surgical navigation

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Functional MRI-guided surgery of intracranial tumors. / Schulder, Michael; Maldjian, Joseph A; Liu, Wen Ching; Mun, In Ki; Carmel, Peter W.

In: Stereotactic and Functional Neurosurgery, Vol. 68, No. 1-4, 01.12.1997, p. 98-105.

Research output: Contribution to journalArticle

Schulder, Michael ; Maldjian, Joseph A ; Liu, Wen Ching ; Mun, In Ki ; Carmel, Peter W. / Functional MRI-guided surgery of intracranial tumors. In: Stereotactic and Functional Neurosurgery. 1997 ; Vol. 68, No. 1-4. pp. 98-105.
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