Further diffusion tensor imaging contribution in horizontal gaze palsy and progressive scoliosis

Maria Conceptión García Otaduy, Claudia Da Costa Leite, Lídia Mayumi Nagae, Marco Da Cunha Pinho, Clarissa Bueno, Umbertina Conti Reed, Fernando Kok

Research output: Contribution to journalArticle

6 Scopus citations


In two siblings with clinical diagnosis of horizontal gaze palsy associated with progressive scoliosis (HGPPS) we could demonstrate by diffusion tensor imaging: (1) An anterior displacement of the transverse pontine fibers; (2) Posterior clumping of the corticospinal, medial lemniscus and central tegmental tracts and of the medial and dorsal longitudinal fasciculi complex; (3) Absent decussation of superior cerebellar peduncle. Those findings can contribute as surrogate markers for the diagnosis.

Original languageEnglish (US)
Pages (from-to)1054-1056
Number of pages3
JournalArquivos de Neuro-Psiquiatria
Issue number4
StatePublished - Dec 1 2009



  • Diffusion
  • MRI
  • Palsy
  • Scoliosis

ASJC Scopus subject areas

  • Clinical Neurology
  • Biological Psychiatry

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