Abstract
The family of heterotrimeric guanine nucleotide-binding regulatory proteins (G proteins) serves an essential role in transducing receptor-generated signals across the plasma membrane. Recent findings reveal unexpected functional roles for individual G protein subunits. Thus, GTP-binding α-subunits and the βγ-subunit complex can influence the activity of effector molecules independently or simultaneously, either synergistically or in opposition, to elicit a complex constellation of cellular events.
Original language | English (US) |
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Pages (from-to) | 383-387 |
Number of pages | 5 |
Journal | Trends in biochemical sciences |
Volume | 17 |
Issue number | 10 |
DOIs | |
State | Published - Oct 1992 |
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology