Gamma knife radiosurgery in the treatment of choroidal neovascularization (wet-type macular degeneration)

Mark A. Henderson, Shailaja Valluri, Simon S. Lo, Thomas C. Witt, Robert M. Worth, Ronald P. Danis, Robert D. Timmerman

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We evaluated retrospectively our institutional experience in the treatment of macular degeneration with gamma knife radiosurgery (GKR). Treatment was delivered in a single shot of 12 Gy. Seven patients were treated between March of 1999 and May of 2000. The median duration of follow-up was 2.2 years. The majority of patients maintained stable visual acuity after treatment. Our series indicates that GKR may be useful as a salvage treatment for patients who have failed or are ineligible for other treatments for their macular degeneration. Further studies are needed to better define the role of GKR in the treatment of macular degeneration.

Original languageEnglish (US)
Pages (from-to)11-17
Number of pages7
JournalStereotactic and Functional Neurosurgery
Volume85
Issue number1
DOIs
StatePublished - Dec 2006

Fingerprint

Wet Macular Degeneration
Choroidal Neovascularization
Radiosurgery
Macular Degeneration
Therapeutics
Salvage Therapy
Visual Acuity

Keywords

  • Choroidal neovascularization
  • Gamma knife
  • Macular degeneration
  • Radiosurgery

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Gamma knife radiosurgery in the treatment of choroidal neovascularization (wet-type macular degeneration). / Henderson, Mark A.; Valluri, Shailaja; Lo, Simon S.; Witt, Thomas C.; Worth, Robert M.; Danis, Ronald P.; Timmerman, Robert D.

In: Stereotactic and Functional Neurosurgery, Vol. 85, No. 1, 12.2006, p. 11-17.

Research output: Contribution to journalArticle

Henderson, Mark A. ; Valluri, Shailaja ; Lo, Simon S. ; Witt, Thomas C. ; Worth, Robert M. ; Danis, Ronald P. ; Timmerman, Robert D. / Gamma knife radiosurgery in the treatment of choroidal neovascularization (wet-type macular degeneration). In: Stereotactic and Functional Neurosurgery. 2006 ; Vol. 85, No. 1. pp. 11-17.
@article{d49ec04282294c7f9888c810ae408083,
title = "Gamma knife radiosurgery in the treatment of choroidal neovascularization (wet-type macular degeneration)",
abstract = "We evaluated retrospectively our institutional experience in the treatment of macular degeneration with gamma knife radiosurgery (GKR). Treatment was delivered in a single shot of 12 Gy. Seven patients were treated between March of 1999 and May of 2000. The median duration of follow-up was 2.2 years. The majority of patients maintained stable visual acuity after treatment. Our series indicates that GKR may be useful as a salvage treatment for patients who have failed or are ineligible for other treatments for their macular degeneration. Further studies are needed to better define the role of GKR in the treatment of macular degeneration.",
keywords = "Choroidal neovascularization, Gamma knife, Macular degeneration, Radiosurgery",
author = "Henderson, {Mark A.} and Shailaja Valluri and Lo, {Simon S.} and Witt, {Thomas C.} and Worth, {Robert M.} and Danis, {Ronald P.} and Timmerman, {Robert D.}",
year = "2006",
month = "12",
doi = "10.1159/000096634",
language = "English (US)",
volume = "85",
pages = "11--17",
journal = "Stereotactic and Functional Neurosurgery",
issn = "1011-6125",
publisher = "S. Karger AG",
number = "1",

}

TY - JOUR

T1 - Gamma knife radiosurgery in the treatment of choroidal neovascularization (wet-type macular degeneration)

AU - Henderson, Mark A.

AU - Valluri, Shailaja

AU - Lo, Simon S.

AU - Witt, Thomas C.

AU - Worth, Robert M.

AU - Danis, Ronald P.

AU - Timmerman, Robert D.

PY - 2006/12

Y1 - 2006/12

N2 - We evaluated retrospectively our institutional experience in the treatment of macular degeneration with gamma knife radiosurgery (GKR). Treatment was delivered in a single shot of 12 Gy. Seven patients were treated between March of 1999 and May of 2000. The median duration of follow-up was 2.2 years. The majority of patients maintained stable visual acuity after treatment. Our series indicates that GKR may be useful as a salvage treatment for patients who have failed or are ineligible for other treatments for their macular degeneration. Further studies are needed to better define the role of GKR in the treatment of macular degeneration.

AB - We evaluated retrospectively our institutional experience in the treatment of macular degeneration with gamma knife radiosurgery (GKR). Treatment was delivered in a single shot of 12 Gy. Seven patients were treated between March of 1999 and May of 2000. The median duration of follow-up was 2.2 years. The majority of patients maintained stable visual acuity after treatment. Our series indicates that GKR may be useful as a salvage treatment for patients who have failed or are ineligible for other treatments for their macular degeneration. Further studies are needed to better define the role of GKR in the treatment of macular degeneration.

KW - Choroidal neovascularization

KW - Gamma knife

KW - Macular degeneration

KW - Radiosurgery

UR - http://www.scopus.com/inward/record.url?scp=33845959502&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33845959502&partnerID=8YFLogxK

U2 - 10.1159/000096634

DO - 10.1159/000096634

M3 - Article

C2 - 17077651

AN - SCOPUS:33845959502

VL - 85

SP - 11

EP - 17

JO - Stereotactic and Functional Neurosurgery

JF - Stereotactic and Functional Neurosurgery

SN - 1011-6125

IS - 1

ER -