Gastrin-secreting tumor of the duodenum (G-cell apudoma, associated with secondary biliary cirrhosis

W. M. Lee, F. Silva, J. B. Price

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

A middle-aged woman with evidence of chronic cholestasis of several years and no previous abdominal surgery was initially thought to have primary biliary cirrhosis. Clinical evaluation disclosed a well-developed secondary biliary cirrhosis apparently caused by extrahepatic obstruction due to a 1 X 2 cm neoplasm of the periampullary duodenum. Electron microscopy and immunofluorescent studies showed the neoplasm to be a G-cell adenoma. Wide local excision has resolved the biliary obstruction. Benign or slow-growing duodenal tumors, if they involve the ampulla of Vater, may produce prolonged partial extrahepatic obstruction and secondary biliary cirrhosis.

Original languageEnglish (US)
Pages (from-to)2596-2601
Number of pages6
JournalCancer
Volume49
Issue number12
StatePublished - 1982

Fingerprint

Apudoma
Gastrin-Secreting Cells
Biliary Liver Cirrhosis
Gastrins
Duodenum
Ampulla of Vater
Neoplasms
Cholestasis
Adenoma
Electron Microscopy

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Gastrin-secreting tumor of the duodenum (G-cell apudoma, associated with secondary biliary cirrhosis. / Lee, W. M.; Silva, F.; Price, J. B.

In: Cancer, Vol. 49, No. 12, 1982, p. 2596-2601.

Research output: Contribution to journalArticle

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