Abstract
The human gastrointestinal tract is colonized with trillions of commensal microbes, and disturbances in the equilibrium of the gut microbiota have now been shown to be associated with a number of human diseases. Fungi, particularly Candida spp., are normal, harmless residents of the human gut, but in certain instances can cause invasive infections and inflammatory disorders. This paper will review the fungal diversity in the human gut, host and fungal factors that regulate GI colonization, and how these factors play into the pathogenesis of human disease.
Original language | English (US) |
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Pages (from-to) | 144-151 |
Number of pages | 8 |
Journal | Current Fungal Infection Reports |
Volume | 7 |
Issue number | 2 |
DOIs | |
State | Published - Jun 2013 |
Keywords
- Candida
- Colonization
- Commensal
- Dectin
- Gastrointestinal
- Inflammatory bowel disease
- Microbiota
- Pathobiont
- Th17
ASJC Scopus subject areas
- Infectious Diseases