Gastrointestinal colonization of fungi

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

The human gastrointestinal tract is colonized with trillions of commensal microbes, and disturbances in the equilibrium of the gut microbiota have now been shown to be associated with a number of human diseases. Fungi, particularly Candida spp., are normal, harmless residents of the human gut, but in certain instances can cause invasive infections and inflammatory disorders. This paper will review the fungal diversity in the human gut, host and fungal factors that regulate GI colonization, and how these factors play into the pathogenesis of human disease.

Original languageEnglish (US)
Pages (from-to)144-151
Number of pages8
JournalCurrent Fungal Infection Reports
Volume7
Issue number2
DOIs
StatePublished - Jun 1 2013

Keywords

  • Candida
  • Colonization
  • Commensal
  • Dectin
  • Gastrointestinal
  • Inflammatory bowel disease
  • Microbiota
  • Pathobiont
  • Th17

ASJC Scopus subject areas

  • Infectious Diseases

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