Gene delivery corrects N-acetylglutamate synthase deficiency and enables insights in the physiological impact of L-arginine activation of N-acetylglutamate synthase

Medicine & Life Sciences

• N-acetyl glutamate synthetase deficiency 100%
• Amino-Acid N-Acetyltransferase 94%
• Arginine 46%
• Hyperammonemia 33%
• Ammonia 28%
• Dependovirus 20%
• Genes 20%
• Mouse Nags protein 19%
• human NAGS protein 18%
• N-carbamylglutamate 16%
• Urea 15%
• Citrulline 10%
• Ligases 9%
• Genetic Therapy 7%
• Knockout Mice 7%
• Central Nervous System 6%
• Animal Models 6%
• Messenger RNA 4%
• Mutation 4%
• Enzymes 4%
• Liver 4%
• Animals 4%
• Proteins 3%