Gene Therapy and Virotherapy of Gliomas

Julius W. Kim, Alan L. Chang, J. Robert Kane, Jacob S. Young, Jian Qiao, MacIej S. Lesniak

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Despite many recent advances in the management of gliomas, such as aggressive surgical resection, chemoradiotherapy, antiangiogenic therapy, and molecular targeted therapy, the survival of patients with high-grade neoplasms remains dismal. Gene therapy and oncolytic virotherapy have emerged as highly promising strategies for treatment of malignant brain tumors due to recent progress in understanding of the underlying cancer biology as well as improved techniques for genetic modification of potential therapeutics.

Original languageEnglish (US)
Pages (from-to)112-123
Number of pages12
JournalProgress in neurological surgery
Volume32
DOIs
StatePublished - Jan 1 2018

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Glioma
Genetic Therapy
Oncolytic Virotherapy
Molecular Targeted Therapy
Genetic Techniques
Chemoradiotherapy
Brain Neoplasms
Neoplasms
Therapeutics
Survival

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Kim, J. W., Chang, A. L., Kane, J. R., Young, J. S., Qiao, J., & Lesniak, M. S. (2018). Gene Therapy and Virotherapy of Gliomas. Progress in neurological surgery, 32, 112-123. https://doi.org/10.1159/000469685

Gene Therapy and Virotherapy of Gliomas. / Kim, Julius W.; Chang, Alan L.; Kane, J. Robert; Young, Jacob S.; Qiao, Jian; Lesniak, MacIej S.

In: Progress in neurological surgery, Vol. 32, 01.01.2018, p. 112-123.

Research output: Contribution to journalArticle

Kim, JW, Chang, AL, Kane, JR, Young, JS, Qiao, J & Lesniak, MS 2018, 'Gene Therapy and Virotherapy of Gliomas', Progress in neurological surgery, vol. 32, pp. 112-123. https://doi.org/10.1159/000469685
Kim JW, Chang AL, Kane JR, Young JS, Qiao J, Lesniak MS. Gene Therapy and Virotherapy of Gliomas. Progress in neurological surgery. 2018 Jan 1;32:112-123. https://doi.org/10.1159/000469685
Kim, Julius W. ; Chang, Alan L. ; Kane, J. Robert ; Young, Jacob S. ; Qiao, Jian ; Lesniak, MacIej S. / Gene Therapy and Virotherapy of Gliomas. In: Progress in neurological surgery. 2018 ; Vol. 32. pp. 112-123.
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