Genetic aspects of male infertility

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Genetic abnormalities may account for 15-30% of male factor infertility. Genes and genomic regulation involved in male genital tract development, gonadal development, and function including those related to spermatogenesis may be involved with male infertility. Although many of the genetic factors are still to be elucidated and many of the predicted genetic perturbations are yet to find their place for clinical applications, it is essential to appraise the current information on genetic basis of male reproductive system disorders.

Original languageEnglish (US)
Title of host publicationMale Infertility: Contemporary Clinical Approaches, Andrology, ART and Antioxidants
PublisherSpringer New York
Pages171-189
Number of pages19
ISBN (Print)9781461433354, 9781461433347
DOIs
Publication statusPublished - Jan 1 2012

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Keywords

  • Genetics in male infertility
  • Genomic regulation of male sexual development
  • Hypospadias
  • Male genital tract development
  • Peritubular myoid cells
  • Sertoli cells
  • Spermatogenesis
  • Spermatogenic genes
  • Testis formation

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Bukulmez, O. (2012). Genetic aspects of male infertility. In Male Infertility: Contemporary Clinical Approaches, Andrology, ART and Antioxidants (pp. 171-189). Springer New York. https://doi.org/10.1007/978-1-4614-3335-4_18