Genetic brain malformations recapitulate phylogeny.

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2 Citations (Scopus)

Abstract

It is generally difficult to establish whether a congenital brain malformation has a genetic basis or is due to other factors. A thesis has been developed, that brain malformations with a genetic basis recapitulate phylogeny. In order to validate this thesis a retrospective CT investigation of brain dysmorphology was carried out in 50 cases of dysgenesis of the corpus callosum, 20 cases of the holoprosencephaly complex, 25 cases of Dandy-Walker malformation, and 50 cases of miscellaneous brain anomalies. This group was compared with 100 neonates with brain damage from acquired causes. The results strongly suggest that a brain malformation that recapitulates phylogeny is very likely to be based on genetic aberration.

Original languageEnglish (US)
Pages (from-to)637-641
Number of pages5
JournalActa Radiologica, Supplement
Volume369
StatePublished - 1986

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Phylogeny
Brain
Dandy-Walker Syndrome
Holoprosencephaly
Agenesis of Corpus Callosum

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Genetic brain malformations recapitulate phylogeny. / Sarwar, M.

In: Acta Radiologica, Supplement, Vol. 369, 1986, p. 637-641.

Research output: Contribution to journalArticle

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