One hundred patients with cirrhosis were compared with control subjects in inherited physical characteristics, colour-blindness, and blood group substances. There was a significant increase among Caucasian cirrhotic subjects with brown hair and very light skin colour compared with controls. Among Negroes an increase in the Duffy blood group was observed in the cirrhotics compared with controls. No increase in colour-blindness was observed in cirrhotic subjects. These studies suggest a broad multifactorial base for susceptibility to cirrhosis and an increased frequency of these factors in Whites compared with non-Whites.
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