Purpose of Review: Pseudoexfoliation is the most common identifiable cause of glaucoma. However, its precise mechanism remains unknown. Recent Findings: Recent studies have shed new light on the genetic factors underlying pseudoexfoliation syndrome, increasing our understanding of the role of the lysyl oxidase-like 1 gene and its various polymorphisms as well as identifying new genetic associations. Recent years have brought new insight on how these genetic factors interact with other factors, including environmental, to confer risk to individuals and populations worldwide. All these findings may hold importance to the screening, diagnosis, and monitoring of pseudoexfoliation and may also help lead to the identification of novel therapeutic targets. Summary: This review serves as an update on the recent trends and findings in pseudoexfoliation syndrome.
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