Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis

Xiang Jing Wang, Yi Jun Yan, Bo Zhang, Jing An, Ji Jia Wang, Jun Tian, Ling Jiang, Yi Hua Chen, Sheng Xiong Huang, Min Yin, Ji Zhang, Ai Li Gao, Chong Xi Liu, Zhao Xiang Zhu, Wen Sheng Xiang

Research output: Contribution to journalShort survey

72 Scopus citations

Abstract

Streptomyces bingchenggensis is a soil-dwelling bacterium producing the commercially important anthelmintic macrolide milbemycins. Besides milbemycins, the insecticidal polyether antibiotic nanchangmycin and some other antibiotics have also been isolated from this strain. Here we report the complete genome sequence of S. bingchenggensis. The availability of the genome sequence of S. bingchenggensis should enable us to understand the biosynthesis of these structurally intricate antibiotics better and facilitate rational improvement of this strain to increase their titers.

Original languageEnglish (US)
Pages (from-to)4526-4527
Number of pages2
JournalJournal of bacteriology
Volume192
Issue number17
DOIs
StatePublished - Sep 1 2010
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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    Wang, X. J., Yan, Y. J., Zhang, B., An, J., Wang, J. J., Tian, J., Jiang, L., Chen, Y. H., Huang, S. X., Yin, M., Zhang, J., Gao, A. L., Liu, C. X., Zhu, Z. X., & Xiang, W. S. (2010). Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis. Journal of bacteriology, 192(17), 4526-4527. https://doi.org/10.1128/JB.00596-10