Genome-wide promoter extraction and analysis in human, mouse, and rat.

Zhenyu Xuan, Fang Zhao, Jinhua Wang, Gengxin Chen, Michael Q. Zhang

Research output: Contribution to journalArticlepeer-review

57 Scopus citations

Abstract

Large-scale and high-throughput genomics research needs reliable and comprehensive genome-wide promoter annotation resources. We have conducted a systematic investigation on how to improve mammalian promoter prediction by incorporating both transcript and conservation information. This enabled us to build a better multispecies promoter annotation pipeline and hence to create CSHLmpd (Cold Spring Harbor Laboratory Mammalian Promoter Database) for the biomedical research community, which can act as a starting reference system for more refined functional annotations.

Original languageEnglish (US)
Pages (from-to)R72
JournalGenome biology
Volume6
Issue number8
StatePublished - 2005
Externally publishedYes

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Cell Biology

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