Genomic Analysis of Salivary Gland Cancer and Treatment of Salivary Gland Cancers

Doreen Palsgrove, Sameer Allahabadi, Saad Khan

Research output: Contribution to journalReview articlepeer-review

Abstract

Salivary gland cancer is a heterogenous group of tumors that presents challenges with both diagnosis and therapy. Recent advances in the classification of salivary gland cancers have led to distinct histologic and genomic criteria that successfully differentiate between cancers with similar clinical behavior and appearance. Genomic abnormalities have led to the emergence of targeted therapies being used in their therapy with drastic improvements in outcomes as well as reductions in treatment-related toxicity. Dramatic results seen with molecular targets, such as HER2, TRK, and others, indicate that this approach has the potential to yield even better treatments for the future.

Original languageEnglish (US)
Pages (from-to)151-163
Number of pages13
JournalSurgical Pathology Clinics
Volume14
Issue number1
DOIs
StatePublished - Mar 2021

Keywords

  • Genomic abnormalities
  • Precision medicine
  • Salivary gland cancer
  • Targeted therapy

ASJC Scopus subject areas

  • Surgery
  • Pathology and Forensic Medicine
  • Medicine(all)

Fingerprint

Dive into the research topics of 'Genomic Analysis of Salivary Gland Cancer and Treatment of Salivary Gland Cancers'. Together they form a unique fingerprint.

Cite this