Global disruption of the WASP autoinhibited structure on Cdc42 binding. Ligand displacement as a novel method for monitoring amide hydrogen exchange

Medicine & Life Sciences

• Wiskott-Aldrich Syndrome Protein 100%
• Amides 76%
• Hydrogen 74%
• GTP Phosphohydrolases 73%
• Ligands 45%
• ras Proteins 6%
• Nucleic Acid Regulatory Sequences 6%
• Polymerization 5%
• Cytoskeleton 5%
• Protein Binding 5%
• Actin Cytoskeleton 5%

Chemical Compounds

• Displacement 52%
• Amide 45%
• Hydrogen 32%
• Effector 30%
• Ligand 28%
• Protein 26%
• Protein Tertiary Structure 11%
• Gibbs Free Energy 6%
• Molecule 6%
• NMR Spectroscopy 6%
• Polymerization Reaction 5%
• Peptide 5%