Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival

Medicine & Life Sciences

• Dual Specificity Phosphatase 1 100%
• Proto-Oncogene Protein c-ets-1 91%
• Glucocorticoid Receptors 73%
• Paclitaxel 66%
• Cell Survival 50%
• Breast Neoplasms 42%
• Dexamethasone 36%
• Breast 30%
• Epithelial Cells 28%
• Tissue Plasminogen Activator 28%
• Phosphotransferases 20%
• Apoptosis 16%
• Gene Expression 15%
• JNK Mitogen-Activated Protein Kinases 14%
• Mitogen-Activated Protein Kinase 1 14%
• Luciferases 12%
• Small Interfering RNA 11%
• Genes 10%
• Phosphorylation 9%
• Cell Line 7%
• Messenger RNA 7%
• Proteins 4%

Chemical Compounds

• Glucocorticoid 85%
• Cell Viability 65%
• Dexamethasone 33%
• Dephosphorylation 33%
• Small Interfering RNA 18%
• Paclitaxel 15%
• Protein 5%