Glucolipotoxicity alters lipid partitioning and causes mitochondrial dysfunction, cholesterol, and ceramide deposition and reactive oxygen species production in INS832/13 β-cells

Wissal El-Assaad, Erik Joly, Annie Barbeau, Robert Sladek, Jean Buteau, Isabel Maestre, Emilie Pepin, Shangang Zhao, José Iglesias, Enrique Roche, Marc Prentki

Research output: Contribution to journalArticlepeer-review

73 Scopus citations
Original languageEnglish (US)
Pages (from-to)3061-3073
Number of pages13
JournalEndocrinology
Volume151
Issue number7
DOIs
StatePublished - Jul 2010
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology

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