Glutathionylation of α-ketoglutarate dehydrogenase: The chemical nature and relative susceptibility of the cofactor lipoic acid to modification

Chemical Compounds

• Lipoic Acid 100%
• Cofactor 65%
• Modification 39%
• Glutathione 32%
• Glutaredoxin 13%
• Adduct 12%
• Inhibition of Enzyme 12%
• Oxidative Stress 8%
• Reaction Half Life 8%
• Disulfide 7%
• Enzyme Activity 7%
• Hydrogen Peroxide 6%
• Calcium(0) 6%
• Catalysis 5%
• Chemistry 5%
• Protein 3%
• Acid 3%

Medicine & Life Sciences

• Thioctic Acid 95%
• Oxidoreductases 65%
• Glutathione 32%
• Disulfides 30%
• Enzymes 27%
• Glutaredoxins 11%
• Heart Mitochondria 10%
• Citric Acid Cycle 8%
• Glutathione Disulfide 8%
• Catalysis 8%
• Hydrogen Peroxide 7%
• Half-Life 6%
• Regeneration 6%
• Mitochondria 5%
• Oxidative Stress 5%
• Calcium 4%
• Proteins 2%