Good neighbours in the tumour stroma reduce oxidative stress

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Tumour cells undergo oncogene-regulated metabolic reprogramming that maximizes survival and growth. However, little is known about metabolic interactions between tumour cells and their non-malignant neighbours in the stroma. Bone-marrow-derived stromal cells are now shown to provide cysteine, an essential nutrient that enables leukaemia cells to resist oxidative stress.

Original languageEnglish (US)
Pages (from-to)235-236
Number of pages2
JournalNature cell biology
Issue number3
StatePublished - Mar 1 2012

ASJC Scopus subject areas

  • Cell Biology


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