@inproceedings{91599b1900a14df483a831dfbf1aa05b,
title = "GPU-based simulation of echocardiography volumes using quantitative fiber-angle-to-backscatter measurements",
abstract = "The intensity of backscattered ultrasound signal from heart muscle is known to be related to the angle between cardiac fibers and the insonification direction. In this work, a GPU-based method of simulating three-dimensional (3D) echocardiographic images from an empirically derived angle-to-backscatter relationship is developed and validated. Images of a rotating fiber phantom are simulated, and it is validated that the angle-to-backscatter relationship is accurately reflected by the simulated envelope data. In a second experiment, echocardiography images are simulated from a diffusion tensor magnetic resonance imaging (DT-MRI) volume of a canine heart to demonstrate that the method produces view-dependent speckle. 3D volumes of a parametrically generated ideal left ventricle phantom are also simulated and processed into fiber orientation maps using the underlying quantitative parameters. Images are simulated based on the characteristics of a 35-by-32 two-dimensional (2D) matrix array probe and a clinical one-dimensional (1D) phased array probe. The processed fiber volumes exhibit good agreement with the virtual phantom{\textquoteright}s ground truth, having an average acute angle error (AAE) of less than 10 degrees for both probes. The simulation method is fast and opens a new approach for ultrasound fiber imaging.",
keywords = "Backscatter, Cardiac fiber orientation, Echocardiography, GPU, Matrix array, Myocardia, Quantification, Ultrasound probe, Ultrasound simulation, Volumetric ultrasound imaging",
author = "Megan Yociss and Baowei Fei",
note = "Funding Information: This research was supported in part by the U.S. National Institutes of Health (NIH) grants (R01CA156775, R01CA204254, R01HL140325, and R21CA231911) and by the Cancer Prevention and Research Institute of Texas (CPRIT) grant RP190588. Publisher Copyright: {\textcopyright} 2021 SPIE; Medical Imaging 2021: Ultrasonic Imaging and Tomography ; Conference date: 15-02-2021 Through 19-02-2021",
year = "2021",
doi = "10.1117/12.2581962",
language = "English (US)",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Byram, {Brett C.} and Ruiter, {Nicole V.}",
booktitle = "Medical Imaging 2021",
}