Graphic display of urinary risk factors for renal stone formation

C. Y C Pak, C. Skurla, J. Harvey

Research output: Contribution to journalArticle

67 Citations (Scopus)

Abstract

From the analysis of various urinary constituents and the estimation of urinary saturation of stone-forming salts, it is now possible to identify risk factors responsible for or contributing to stone formation. Metabolic factors included calcium, oxalate, uric acid, citrate and pH. Environmental factors were total volume, sodium, sulfate, phosphate and magnesium. Physicochemical factors represented saturation of calcium oxalate, brushite, monosodium urate, struvite and uric acid. A scheme for graphic display of risk factors was developed to allow ready visual recognition of important risk factors presumed to cause stone formation. This graphic display had diagnostic use as well as practical value in following response to treatment. For example, a low urinary pH and high urinary concentration of undissociated uric acid could be discerned readily in cases of uric acid lithiasis, as were high urinary pH and exaggerated urinary supersaturation of struvite in cases of infection lithiasis. In a patient with absorptive hypercalcuria and hypocitraturia treatment with thiazide and potassium citrate could be shown to abolish high risks (hypercalciuria, hypocitraturia and relative supersaturation of calcium oxalate) displayed before treatment.

Original languageEnglish (US)
Pages (from-to)867-870
Number of pages4
JournalJournal of Urology
Volume134
Issue number5
StatePublished - 1985

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Uric Acid
Calcium Oxalate
Kidney
Lithiasis
Potassium Citrate
Thiazides
Hypercalciuria
Urinary Calculi
Citric Acid
Magnesium
Therapeutics
Salts
Infection
Struvite

ASJC Scopus subject areas

  • Urology

Cite this

Graphic display of urinary risk factors for renal stone formation. / Pak, C. Y C; Skurla, C.; Harvey, J.

In: Journal of Urology, Vol. 134, No. 5, 1985, p. 867-870.

Research output: Contribution to journalArticle

Pak, CYC, Skurla, C & Harvey, J 1985, 'Graphic display of urinary risk factors for renal stone formation', Journal of Urology, vol. 134, no. 5, pp. 867-870.
Pak, C. Y C ; Skurla, C. ; Harvey, J. / Graphic display of urinary risk factors for renal stone formation. In: Journal of Urology. 1985 ; Vol. 134, No. 5. pp. 867-870.
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