Fifty-three infants 0—6 months of age with abnormal 24-h intraesophageal pH monitoring were evaluated by esophageal suction biopsies and endoscopie grasp biopsies. Histologie esophagitis was present in 30% of the infants. Of the infants with esophagitis, 88% were accurately identified by suction biopsy, and 75% were accurately identified by endoscopie grasp biopsy. Suction bi- opsy alone was not significantly different from combined grasp and suction biopsy, while differences between grasp biopsy and combined biopsy approached significance (p = 0.051). Twelve clinical symptoms and 21 intraesophageal pH monitoring parameters were evaluated for their ability to predict esophagitis, and none were found to be useful. We conclude that endoscopie esophageal biopsy, while more costly, offers no advantage over suction biopsy for the detection of esophagitis in young infants.
|Original language||English (US)|
|Number of pages||5|
|Journal||Journal of pediatric gastroenterology and nutrition|
|State||Published - Apr 1995|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health