Guidelines for the early management of adults with ischemic stroke: A guideline from the American heart association/American stroke association stroke council, clinical cardiology council, cardiovascular radiology and intervention council, and the atherosclerotic peripheral vascular disease and quality of care outcomes in research interdisciplinary working groups:

Harold P. Adams, Gregory Del Zoppo, Mark J. Alberts, Deepak L. Bhatt, Lawrence Brass, Anthony Furlan, Robert L. Grubb, Randall T. Higashida, Edward C. Jauch, Chelsea Kidwell, Patrick D. Lyden, Lewis B. Morgenstern, Adnan I. Qureshi, Robert H. Rosenwasser, Phillip A. Scott, Eelco F M Wijdicks

Research output: Contribution to journalArticle

1744 Citations (Scopus)

Abstract

PURPOSE - Our goal is to provide an overview of the current evidence about components of the evaluation and treatment of adults with acute ischemic stroke. The intended audience is physicians and other emergency healthcare providers who treat patients within the first 48 hours after stroke. In addition, information for healthcare policy makers is included. METHODS - Members of the panel were appointed by the American Heart Association Stroke Council's Scientific Statement Oversight Committee and represented different areas of expertise. The panel reviewed the relevant literature with an emphasis on reports published since 2003 and used the American Heart Association Stroke Council's Levels of Evidence grading algorithm to rate the evidence and to make recommendations. After approval of the statement by the panel, it underwent peer review and approval by the American Heart Association Science Advisory and Coordinating Committee. It is intended that this guideline be fully updated in 3 years. RESULTS - Management of patients with acute ischemic stroke remains multifaceted and includes several aspects of care that have not been tested in clinical trials. This statement includes recommendations for management from the first contact by emergency medical services personnel through initial admission to the hospital. Intravenous administration of recombinant tissue plasminogen activator remains the most beneficial proven intervention for emergency treatment of stroke. Several interventions, including intra-arterial administration of thrombolytic agents and mechanical interventions, show promise. Because many of the recommendations are based on limited data, additional research on treatment of acute ischemic stroke is needed.

Original languageEnglish (US)
Pages (from-to)1655-1711
Number of pages57
JournalStroke
Volume38
Issue number5
DOIs
StatePublished - May 2007

Fingerprint

American Heart Association
Peripheral Vascular Diseases
Quality of Health Care
Cardiology
Radiology
Stroke
Outcome Assessment (Health Care)
Guidelines
Peer Review
Fibrinolytic Agents
Emergency Treatment
Emergency Medical Services
Tissue Plasminogen Activator
Advisory Committees
Administrative Personnel
Intravenous Administration
Health Personnel
Emergencies
Clinical Trials
Delivery of Health Care

Keywords

  • Acute cerebral infarction
  • AHA Scientific Statements
  • Emergency medical services
  • Stroke
  • Tissue plasminogen activator

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Neuroscience(all)

Cite this

Guidelines for the early management of adults with ischemic stroke : A guideline from the American heart association/American stroke association stroke council, clinical cardiology council, cardiovascular radiology and intervention council, and the atherosclerotic peripheral vascular disease and quality of care outcomes in research interdisciplinary working groups: / Adams, Harold P.; Del Zoppo, Gregory; Alberts, Mark J.; Bhatt, Deepak L.; Brass, Lawrence; Furlan, Anthony; Grubb, Robert L.; Higashida, Randall T.; Jauch, Edward C.; Kidwell, Chelsea; Lyden, Patrick D.; Morgenstern, Lewis B.; Qureshi, Adnan I.; Rosenwasser, Robert H.; Scott, Phillip A.; Wijdicks, Eelco F M.

In: Stroke, Vol. 38, No. 5, 05.2007, p. 1655-1711.

Research output: Contribution to journalArticle

Adams, Harold P. ; Del Zoppo, Gregory ; Alberts, Mark J. ; Bhatt, Deepak L. ; Brass, Lawrence ; Furlan, Anthony ; Grubb, Robert L. ; Higashida, Randall T. ; Jauch, Edward C. ; Kidwell, Chelsea ; Lyden, Patrick D. ; Morgenstern, Lewis B. ; Qureshi, Adnan I. ; Rosenwasser, Robert H. ; Scott, Phillip A. ; Wijdicks, Eelco F M. / Guidelines for the early management of adults with ischemic stroke : A guideline from the American heart association/American stroke association stroke council, clinical cardiology council, cardiovascular radiology and intervention council, and the atherosclerotic peripheral vascular disease and quality of care outcomes in research interdisciplinary working groups:. In: Stroke. 2007 ; Vol. 38, No. 5. pp. 1655-1711.
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AU - Del Zoppo, Gregory

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AU - Bhatt, Deepak L.

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AU - Grubb, Robert L.

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AU - Jauch, Edward C.

AU - Kidwell, Chelsea

AU - Lyden, Patrick D.

AU - Morgenstern, Lewis B.

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