H-scan sensitivity to scattering size

Mawia Khairalseed, Kenneth Hoyt, Juvenal Ormachea, Alberto Terrazas, Kevin J. Parker

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

In the H-scan analysis and display, visualization of different scattering sizes and types is enabled by a matched filter approach involving different orders of Gaussian weighted Hermite functions. An important question with respect to clinical applications involves the change in H-scan outputs with respect to small changes in scatterer sizes. The sensitivity of H-scan outputs is analyzed using the theory of backscatter from a compressible sphere. Experimental corroboration is established using mono dispersed spherical scatterers in phantoms. With a 6-MHz center frequency broadband transducer, it is possible to visualize changes in scattering size in the order of 10 to 15 μm in phantoms and also changes in ex vivo bovine liver tissue due to edema caused by hypotonic perfusion.

Original languageEnglish (US)
Article number043501
JournalJournal of Medical Imaging
Volume4
Issue number4
DOIs
StatePublished - Oct 1 2017

Keywords

  • Rayleigh scattering
  • scattering
  • tissue characterization
  • ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Khairalseed, M., Hoyt, K., Ormachea, J., Terrazas, A., & Parker, K. J. (2017). H-scan sensitivity to scattering size. Journal of Medical Imaging, 4(4), [043501]. https://doi.org/10.1117/1.JMI.4.4.043501