Abstract
On December 22, 1988, a second conjugate vaccine was licensed by the US Food and Drug Administration for the prevention of infections caused by H influenzae type b in children 18 months of age or older. This newly licensed vaccine is a conjugate of H influenzae type b capsular oligosaccharide and a nontoxic mutant diphtheria toxin protein molecule called CRM197. The official designation of this vaccine is 'Haemophilus b conjugate vaccine (diphtheria CRM197 protein conjugate)' and it is often referred to as HbOC.
Original language | English (US) |
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Pages (from-to) | 386-387 |
Number of pages | 2 |
Journal | Pediatrics |
Volume | 84 |
Issue number | 2 |
State | Published - 1989 |
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health