Healthcare-associated Legionnaires’ disease: Limitations of surveillance definitions and importance of epidemiologic investigation

Laila M. Castellino, Shantini D. Gamage, Patti V. Hoffman, Stephen M. Kralovic, Mark Holodniy, Jack M. Bernstein, Gary A. Roselle

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Healthcare-associated Legionnaires’ disease (HCA LD) causes significant morbidity and mortality, with varying guidance on prevention. We describe the evaluation of a case of possible HCA LD and note the pitfalls of relying solely on an epidemiologic definition for association of a case with a facility. Our detailed investigation led to the identification of a new Legionella pneumophila serogroup 1 sequence type, confirmed a healthcare association and helped build the framework for our ongoing preventive efforts. Our experience highlights the role of routine environmental cultures in the assessment of risk for a given facility. As clinicians increasingly rely on urinary antigen testing for the detection of L. pneumophila, our investigation emphasises the importance of clinical cultures in an epidemiologic investigation.

Original languageEnglish (US)
Pages (from-to)307-310
Number of pages4
JournalJournal of Infection Prevention
Volume18
Issue number6
DOIs
StatePublished - Nov 1 2017
Externally publishedYes

Fingerprint

Legionnaires' Disease
Legionella pneumophila
Delivery of Health Care
Morbidity
Antigens
Mortality

Keywords

  • epidemiology
  • healthcare-associated infections
  • Legionella

ASJC Scopus subject areas

  • Health Policy
  • Public Health, Environmental and Occupational Health
  • Advanced and Specialized Nursing
  • Infectious Diseases

Cite this

Healthcare-associated Legionnaires’ disease : Limitations of surveillance definitions and importance of epidemiologic investigation. / Castellino, Laila M.; Gamage, Shantini D.; Hoffman, Patti V.; Kralovic, Stephen M.; Holodniy, Mark; Bernstein, Jack M.; Roselle, Gary A.

In: Journal of Infection Prevention, Vol. 18, No. 6, 01.11.2017, p. 307-310.

Research output: Contribution to journalArticle

Castellino, Laila M. ; Gamage, Shantini D. ; Hoffman, Patti V. ; Kralovic, Stephen M. ; Holodniy, Mark ; Bernstein, Jack M. ; Roselle, Gary A. / Healthcare-associated Legionnaires’ disease : Limitations of surveillance definitions and importance of epidemiologic investigation. In: Journal of Infection Prevention. 2017 ; Vol. 18, No. 6. pp. 307-310.
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