The Hedgehog (Hh) signaling pathway is essential for development and tissue homeostasis in metazoans. Probably as a result of its potent influence on cell-fate outcomes, the Hh pathway when corrupted results in malformations and diseases such as cancer. Many of the pathway components that contribute to Hh-mediated signal transduction are presented.
|Original language||English (US)|
|Journal||Science's STKE : signal transduction knowledge environment|
|State||Published - Oct 9 2007|
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