Hematologic recovery and deterioration after 'successful' radiotherapy for Hodgkin's disease

R. E. Johnson, L. E. Kun, J. A. Belladonna, S. K. Johnson, H. D. Brereton, G. A. Cohen

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Long term hematological profiles were compiled for 50 consecutive patients who remained continuously free of Hodgkin's disease, more than 5 yr after nodal irradiation. Return of peripheral blood values to normal occurred consistently, and recovery has been sustained over the years of observation. In the entire series of 180 cases, only 7 patients have experienced a hematological deterioration in the absence of further marrow suppressive therapy. Intervals from initial treatment to hematological deterioration ranged from several weeks to more than 5 yr. In 3 cases the cause could not be established before death. There was eventual histological confirmation of recurrent Hodgkin's disease in 6 of the 7 patients. Unexplained depression of peripheral blood counts after completion of radiotherapy should be interpreted as presumptive evidence for recurrent disease.

Original languageEnglish (US)
Pages (from-to)213-216
Number of pages4
JournalUnknown Journal
Volume80
Issue number2
DOIs
StatePublished - Jan 1 1974

ASJC Scopus subject areas

  • Internal Medicine

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    Johnson, R. E., Kun, L. E., Belladonna, J. A., Johnson, S. K., Brereton, H. D., & Cohen, G. A. (1974). Hematologic recovery and deterioration after 'successful' radiotherapy for Hodgkin's disease. Unknown Journal, 80(2), 213-216. https://doi.org/10.7326/0003-4819-80-2-213