Hemodynamic alterations during septal or right ventricular ischemia in dogs

David E Fixler; George A. Monroe; James M. Wheeler

doi:10.1016/S0002-8703(77)80313-X

Hemodynamic alterations during septal or right ventricular ischemia in dogs

David E Fixler, George A. Monroe, James M. Wheeler

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

This study indicates that in dogs, ischemic injury to just the ventricular septum has little effect on left ventricular function. The data demonstrate that ischemic injury to either the right ventricular free wall or the ventricular septum alters right ventricular function and/or compliance, suggesting that both regions play a role in maintaining right ventricular performance. That septal contraction supports right ventricular function may explain why in earlier studies, right ventricular pressure development and output were little affected by severe injury to the free wall.

Original language	English (US)
Pages (from-to)	210-215
Number of pages	6
Journal	American heart journal
Volume	93
Issue number	2
DOIs	https://doi.org/10.1016/S0002-8703(77)80313-X
State	Published - Feb 1977

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/S0002-8703(77)80313-X

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title = "Hemodynamic alterations during septal or right ventricular ischemia in dogs",

abstract = "This study indicates that in dogs, ischemic injury to just the ventricular septum has little effect on left ventricular function. The data demonstrate that ischemic injury to either the right ventricular free wall or the ventricular septum alters right ventricular function and/or compliance, suggesting that both regions play a role in maintaining right ventricular performance. That septal contraction supports right ventricular function may explain why in earlier studies, right ventricular pressure development and output were little affected by severe injury to the free wall.",

author = "Fixler, {David E} and Monroe, {George A.} and Wheeler, {James M.}",

note = "Funding Information: From the Department of Pediatrics, The University of Texas Health Science Center at Dallas, Southwestern Medical School, Dallas, Texas. This study was supported by a grant from the American Heart Association, Texas Affiliate, Inc. Received for publication Dec. 17, 1975. Reprint requests: David E. Fixler, M.D., Department of Pediatrics, The University of Texas Health Science Center at Dallas, Dallas, Texas 75235.",

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T1 - Hemodynamic alterations during septal or right ventricular ischemia in dogs

AU - Fixler, David E

AU - Monroe, George A.

AU - Wheeler, James M.

N1 - Funding Information: From the Department of Pediatrics, The University of Texas Health Science Center at Dallas, Southwestern Medical School, Dallas, Texas. This study was supported by a grant from the American Heart Association, Texas Affiliate, Inc. Received for publication Dec. 17, 1975. Reprint requests: David E. Fixler, M.D., Department of Pediatrics, The University of Texas Health Science Center at Dallas, Dallas, Texas 75235.

PY - 1977/2

Y1 - 1977/2

N2 - This study indicates that in dogs, ischemic injury to just the ventricular septum has little effect on left ventricular function. The data demonstrate that ischemic injury to either the right ventricular free wall or the ventricular septum alters right ventricular function and/or compliance, suggesting that both regions play a role in maintaining right ventricular performance. That septal contraction supports right ventricular function may explain why in earlier studies, right ventricular pressure development and output were little affected by severe injury to the free wall.

AB - This study indicates that in dogs, ischemic injury to just the ventricular septum has little effect on left ventricular function. The data demonstrate that ischemic injury to either the right ventricular free wall or the ventricular septum alters right ventricular function and/or compliance, suggesting that both regions play a role in maintaining right ventricular performance. That septal contraction supports right ventricular function may explain why in earlier studies, right ventricular pressure development and output were little affected by severe injury to the free wall.

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Hemodynamic alterations during septal or right ventricular ischemia in dogs

Abstract

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