Hepatic decompensation in patients with HIV/Hepatitis B Virus (HBV)/Hepatitis C Virus (HCV) triple infection versus HIV/HCV coinfection and the effect of Anti-HBV Nucleos(t)ide therapy

Vincent Lo Re; Li Wang; Scott Devine; Onur Baser; Temitope Olufade

doi:10.1093/cid/ciu476

Hepatic decompensation in patients with HIV/Hepatitis B Virus (HBV)/Hepatitis C Virus (HCV) triple infection versus HIV/HCV coinfection and the effect of Anti-HBV Nucleos(t)ide therapy

Vincent Lo Re, Li Wang, Scott Devine, Onur Baser, Temitope Olufade

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

The incidence rate of hepatic decompensation was higher in patients with human immunodeficiency virus (HIV)/hepatitis B virus (HBV)/hepatitis C virus (HCV) triple infection than in those with HIV/HCV coinfection (24.1 vs 10.8 events per 1000 person-years; hazard ratio [HR], 1.89; 95% confidence interval [CI], 1.12-3.18). Compared with HIV/HCVinfected patients, the rate of decompensation was increased among HIV/HBV/HCV-infected patients receiving no anti- HBV therapy (HR, 2.48; 95% CI, 1.37-4.49) but not among those who did receive such therapy (HR, 1.09; 95% CI, .40-2.97).

Original language	English (US)
Pages (from-to)	1027-1031
Number of pages	5
Journal	Clinical Infectious Diseases
Volume	59
Issue number	7
DOIs	https://doi.org/10.1093/cid/ciu476
State	Published - Oct 1 2014
Externally published	Yes

Keywords

End-stage liver disease
HIV
Hepatic decompensation
Hepatitis B
Hepatitis C

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

Access to Document

10.1093/cid/ciu476

Cite this

Hepatic decompensation in patients with HIV/Hepatitis B Virus (HBV)/Hepatitis C Virus (HCV) triple infection versus HIV/HCV coinfection and the effect of Anti-HBV Nucleos(t)ide therapy. / Re, Vincent Lo; Wang, Li; Devine, Scott et al.
In: Clinical Infectious Diseases, Vol. 59, No. 7, 01.10.2014, p. 1027-1031.

Research output: Contribution to journal › Article › peer-review

@article{71fde90640144d9ea291f5f5a08f8967,

title = "Hepatic decompensation in patients with HIV/Hepatitis B Virus (HBV)/Hepatitis C Virus (HCV) triple infection versus HIV/HCV coinfection and the effect of Anti-HBV Nucleos(t)ide therapy",

abstract = "The incidence rate of hepatic decompensation was higher in patients with human immunodeficiency virus (HIV)/hepatitis B virus (HBV)/hepatitis C virus (HCV) triple infection than in those with HIV/HCV coinfection (24.1 vs 10.8 events per 1000 person-years; hazard ratio [HR], 1.89; 95% confidence interval [CI], 1.12-3.18). Compared with HIV/HCVinfected patients, the rate of decompensation was increased among HIV/HBV/HCV-infected patients receiving no anti- HBV therapy (HR, 2.48; 95% CI, 1.37-4.49) but not among those who did receive such therapy (HR, 1.09; 95% CI, .40-2.97).",

keywords = "End-stage liver disease, HIV, Hepatic decompensation, Hepatitis B, Hepatitis C",

author = "Re, {Vincent Lo} and Li Wang and Scott Devine and Onur Baser and Temitope Olufade",

note = "Publisher Copyright: {\textcopyright} 2014 The Author.",

year = "2014",

month = oct,

day = "1",

doi = "10.1093/cid/ciu476",

language = "English (US)",

volume = "59",

pages = "1027--1031",

journal = "Clinical Infectious Diseases",

issn = "1058-4838",

publisher = "Oxford University Press",

number = "7",

}

TY - JOUR

T1 - Hepatic decompensation in patients with HIV/Hepatitis B Virus (HBV)/Hepatitis C Virus (HCV) triple infection versus HIV/HCV coinfection and the effect of Anti-HBV Nucleos(t)ide therapy

AU - Re, Vincent Lo

AU - Wang, Li

AU - Devine, Scott

AU - Baser, Onur

AU - Olufade, Temitope

PY - 2014/10/1

Y1 - 2014/10/1

N2 - The incidence rate of hepatic decompensation was higher in patients with human immunodeficiency virus (HIV)/hepatitis B virus (HBV)/hepatitis C virus (HCV) triple infection than in those with HIV/HCV coinfection (24.1 vs 10.8 events per 1000 person-years; hazard ratio [HR], 1.89; 95% confidence interval [CI], 1.12-3.18). Compared with HIV/HCVinfected patients, the rate of decompensation was increased among HIV/HBV/HCV-infected patients receiving no anti- HBV therapy (HR, 2.48; 95% CI, 1.37-4.49) but not among those who did receive such therapy (HR, 1.09; 95% CI, .40-2.97).

AB - The incidence rate of hepatic decompensation was higher in patients with human immunodeficiency virus (HIV)/hepatitis B virus (HBV)/hepatitis C virus (HCV) triple infection than in those with HIV/HCV coinfection (24.1 vs 10.8 events per 1000 person-years; hazard ratio [HR], 1.89; 95% confidence interval [CI], 1.12-3.18). Compared with HIV/HCVinfected patients, the rate of decompensation was increased among HIV/HBV/HCV-infected patients receiving no anti- HBV therapy (HR, 2.48; 95% CI, 1.37-4.49) but not among those who did receive such therapy (HR, 1.09; 95% CI, .40-2.97).

KW - End-stage liver disease

KW - HIV

KW - Hepatic decompensation

KW - Hepatitis B

KW - Hepatitis C

UR - http://www.scopus.com/inward/record.url?scp=84929942627&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84929942627&partnerID=8YFLogxK

U2 - 10.1093/cid/ciu476

DO - 10.1093/cid/ciu476

M3 - Article

C2 - 24944235

AN - SCOPUS:84929942627

SN - 1058-4838

VL - 59

SP - 1027

EP - 1031

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

IS - 7

ER -

Hepatic decompensation in patients with HIV/Hepatitis B Virus (HBV)/Hepatitis C Virus (HCV) triple infection versus HIV/HCV coinfection and the effect of Anti-HBV Nucleos(t)ide therapy

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this