Hepatic infarction associated with eclampsia

K. J. Krueger, B. J. Hoffman, W. M. Lee

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Pregnancy-related liver diseases are complex in presentation and oftentimes confusing to clinicians, leading to misdiagnoses and unwarranted or delayed therapies. The exact pathogenesis of these disorders and their relationship to pre-eclampsia/eclampsia is unclear, thus making categorization difficult. We present a patient who in the third trimester of pregnancy developed severe abdominal pain, fever and transaminases greater than 30 times normal. The patient's laboratory data, abdominal CT scan, abdominal MRI scan, liver-spleen scan and liver biopsy performed 28 days postpartum subsequently confirmed the diagnosis of hepatic infarction. Hepatic infarction is a rare complication of late pregnancy usually associated with severe eclampsia that has distinctive histologic and laboratory findings. Recognition of infarction as a separate entity among the spectrum of the pregnancy-related liver disorders should help avoid unneeded delay in diagnosis or inapropriate treatment of these critically ill patients.

Original languageEnglish (US)
Pages (from-to)588-592
Number of pages5
JournalAmerican Journal of Gastroenterology
Volume85
Issue number5
StatePublished - 1990

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Eclampsia
Infarction
Liver
Pregnancy
Pregnancy Complications
Third Pregnancy Trimester
Pre-Eclampsia
Transaminases
Diagnostic Errors
Critical Illness
Postpartum Period
Abdominal Pain
Liver Diseases
Fever
Spleen
Magnetic Resonance Imaging
Biopsy
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Hepatic infarction associated with eclampsia. / Krueger, K. J.; Hoffman, B. J.; Lee, W. M.

In: American Journal of Gastroenterology, Vol. 85, No. 5, 1990, p. 588-592.

Research output: Contribution to journalArticle

Krueger, KJ, Hoffman, BJ & Lee, WM 1990, 'Hepatic infarction associated with eclampsia', American Journal of Gastroenterology, vol. 85, no. 5, pp. 588-592.
Krueger, K. J. ; Hoffman, B. J. ; Lee, W. M. / Hepatic infarction associated with eclampsia. In: American Journal of Gastroenterology. 1990 ; Vol. 85, No. 5. pp. 588-592.
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