Hepatitis A epidemic in the elderly

Geri R. Brown, Kim Persley

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Background. The purpose of this study was to characterize acute hepatitis A in patients more than 40 years old. Methods. Retrospective chart reviews and physician questionnaires were used. Hospitalization, laboratory tests, comorbid conditions, complications, and mortality were assessed. Results. A total of 180 cases of acute hepatitis A occurred in patients more than age 40. Hospitalization rates increased from 3% for the group aged 40 to 49 to 12% in the group aged 50 to 69 and 42% in those ≥70 years old. The mean peak total bilirubin value was higher in hospitalized patients than in nonhospitalized patients (12.4 mg/dL vs 7.7 mg/dL). Comorbid conditions included significant alcohol consumption (8%), diabetes (16.6%), cardiovascular disease (54%), and chronic obstructive pulmonary disease (COPD) (21%). Complications included pancreatitis (4.1%), ascites (8.3%), prolonged cholestatic features (7.6%), and death (0.8%). Conclusion. Hospitalization rates and rare complications associated with acute hepatitis A increase with age.

Original languageEnglish (US)
Pages (from-to)826-833
Number of pages8
JournalSouthern Medical Journal
Volume95
Issue number8
StatePublished - 2002

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Hepatitis A
Hospitalization
Bilirubin
Ascites
Alcohol Drinking
Pancreatitis
Chronic Obstructive Pulmonary Disease
Cardiovascular Diseases
Physicians
Mortality

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hepatitis A epidemic in the elderly. / Brown, Geri R.; Persley, Kim.

In: Southern Medical Journal, Vol. 95, No. 8, 2002, p. 826-833.

Research output: Contribution to journalArticle

Brown, GR & Persley, K 2002, 'Hepatitis A epidemic in the elderly', Southern Medical Journal, vol. 95, no. 8, pp. 826-833.
Brown, Geri R. ; Persley, Kim. / Hepatitis A epidemic in the elderly. In: Southern Medical Journal. 2002 ; Vol. 95, No. 8. pp. 826-833.
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