Hepatocellular carcinoma and other liver lesions

Reena Salgia; Amit G. Singal

doi:10.1016/j.mcna.2013.09.003

Hepatocellular carcinoma and other liver lesions

Reena Salgia, Amit G. Singal

Research output: Contribution to journal › Review article › peer-review

13 Scopus citations

Abstract

Patients with cirrhosis are at greatest risk for development of hepatocellular carcinoma (HCC) and should undergo semiannual surveillance using ultrasound, with or without alpha fetoprotein. Patients with positive surveillance testing should undergo contrast-enhanced MRI or 4-phase CT for diagnostic evaluation. There are therapeutic options for most patients with any tumor stage; however, treatment decisions must be individualized after accounting for degree of liver dysfunction and patient performance status. A multidisciplinary approach to care is recommended for optimal communication and treatment delivery. The aim of this review is to provide an up-to-date summary of the diagnosis and management of HCC.

Original language	English (US)
Pages (from-to)	103-118
Number of pages	16
Journal	Medical Clinics of North America
Volume	98
Issue number	1
DOIs	https://doi.org/10.1016/j.mcna.2013.09.003
State	Published - Jan 1 2014

Keywords

Diagnosis
Liver cancer
Liver mass
Treatment

ASJC Scopus subject areas

Medicine(all)

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title = "Hepatocellular carcinoma and other liver lesions",

abstract = "Patients with cirrhosis are at greatest risk for development of hepatocellular carcinoma (HCC) and should undergo semiannual surveillance using ultrasound, with or without alpha fetoprotein. Patients with positive surveillance testing should undergo contrast-enhanced MRI or 4-phase CT for diagnostic evaluation. There are therapeutic options for most patients with any tumor stage; however, treatment decisions must be individualized after accounting for degree of liver dysfunction and patient performance status. A multidisciplinary approach to care is recommended for optimal communication and treatment delivery. The aim of this review is to provide an up-to-date summary of the diagnosis and management of HCC.",

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AB - Patients with cirrhosis are at greatest risk for development of hepatocellular carcinoma (HCC) and should undergo semiannual surveillance using ultrasound, with or without alpha fetoprotein. Patients with positive surveillance testing should undergo contrast-enhanced MRI or 4-phase CT for diagnostic evaluation. There are therapeutic options for most patients with any tumor stage; however, treatment decisions must be individualized after accounting for degree of liver dysfunction and patient performance status. A multidisciplinary approach to care is recommended for optimal communication and treatment delivery. The aim of this review is to provide an up-to-date summary of the diagnosis and management of HCC.

KW - Diagnosis

KW - Liver cancer

KW - Liver mass

KW - Treatment

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