Abstract
Patients with cirrhosis are at greatest risk for development of hepatocellular carcinoma (HCC) and should undergo semiannual surveillance using ultrasound, with or without alpha fetoprotein. Patients with positive surveillance testing should undergo contrast-enhanced MRI or 4-phase CT for diagnostic evaluation. There are therapeutic options for most patients with any tumor stage; however, treatment decisions must be individualized after accounting for degree of liver dysfunction and patient performance status. A multidisciplinary approach to care is recommended for optimal communication and treatment delivery. The aim of this review is to provide an up-to-date summary of the diagnosis and management of HCC.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 103-118 |
| Number of pages | 16 |
| Journal | Medical Clinics of North America |
| Volume | 98 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2014 |
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Keywords
- Diagnosis
- Liver cancer
- Liver mass
- Treatment
ASJC Scopus subject areas
- Medicine(all)
Cite this
Hepatocellular carcinoma and other liver lesions. / Salgia, Reena; Singal, Amit G.
In: Medical Clinics of North America, Vol. 98, No. 1, 01.2014, p. 103-118.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Hepatocellular carcinoma and other liver lesions
AU - Salgia, Reena
AU - Singal, Amit G.
PY - 2014/1
Y1 - 2014/1
N2 - Patients with cirrhosis are at greatest risk for development of hepatocellular carcinoma (HCC) and should undergo semiannual surveillance using ultrasound, with or without alpha fetoprotein. Patients with positive surveillance testing should undergo contrast-enhanced MRI or 4-phase CT for diagnostic evaluation. There are therapeutic options for most patients with any tumor stage; however, treatment decisions must be individualized after accounting for degree of liver dysfunction and patient performance status. A multidisciplinary approach to care is recommended for optimal communication and treatment delivery. The aim of this review is to provide an up-to-date summary of the diagnosis and management of HCC.
AB - Patients with cirrhosis are at greatest risk for development of hepatocellular carcinoma (HCC) and should undergo semiannual surveillance using ultrasound, with or without alpha fetoprotein. Patients with positive surveillance testing should undergo contrast-enhanced MRI or 4-phase CT for diagnostic evaluation. There are therapeutic options for most patients with any tumor stage; however, treatment decisions must be individualized after accounting for degree of liver dysfunction and patient performance status. A multidisciplinary approach to care is recommended for optimal communication and treatment delivery. The aim of this review is to provide an up-to-date summary of the diagnosis and management of HCC.
KW - Diagnosis
KW - Liver cancer
KW - Liver mass
KW - Treatment
UR - http://www.scopus.com/inward/record.url?scp=84888018764&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84888018764&partnerID=8YFLogxK
U2 - 10.1016/j.mcna.2013.09.003
DO - 10.1016/j.mcna.2013.09.003
M3 - Article
C2 - 24266917
AN - SCOPUS:84888018764
VL - 98
SP - 103
EP - 118
JO - Medical Clinics of North America
JF - Medical Clinics of North America
SN - 0025-7125
IS - 1
ER -