Hepoxilins B3

Synthesis of all four stereoisomers and a glutathione adduct

Yuri Y. Belosludtsev, R. Omindine Kollah, J R Falck, Jorge H. Capdevila

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Utilizing (-)-quinic acid as a differentiated bis-aldehyde chiron, both pairs of hepoxilin B3 enantiomers and a glutathione adduct were synthesized by regiospecific functionalization of an acyclic vic-diol.

Original languageEnglish (US)
Pages (from-to)5327-5330
Number of pages4
JournalTetrahedron Letters
Volume35
Issue number30
DOIs
StatePublished - Jul 25 1994

Fingerprint

Quinic Acid
Stereoisomerism
Enantiomers
Aldehydes
Glutathione
10-hydroxy-11,12-epoxyeicosa-5,8,14-trienoic acid
chiron

Keywords

  • (-)-quinic acid
  • eicosanoid
  • epoxy-alcohol
  • oxiranyl-carbinol
  • Wittig

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Hepoxilins B3 : Synthesis of all four stereoisomers and a glutathione adduct. / Belosludtsev, Yuri Y.; Kollah, R. Omindine; Falck, J R; Capdevila, Jorge H.

In: Tetrahedron Letters, Vol. 35, No. 30, 25.07.1994, p. 5327-5330.

Research output: Contribution to journalArticle

Belosludtsev, Yuri Y. ; Kollah, R. Omindine ; Falck, J R ; Capdevila, Jorge H. / Hepoxilins B3 : Synthesis of all four stereoisomers and a glutathione adduct. In: Tetrahedron Letters. 1994 ; Vol. 35, No. 30. pp. 5327-5330.
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