Hepoxilins B3: Synthesis of all four stereoisomers and a glutathione adduct

Yuri Y. Belosludtsev, R. Omindine Kollah, J R Falck, Jorge H. Capdevila

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Utilizing (-)-quinic acid as a differentiated bis-aldehyde chiron, both pairs of hepoxilin B3 enantiomers and a glutathione adduct were synthesized by regiospecific functionalization of an acyclic vic-diol.

Original languageEnglish (US)
Pages (from-to)5327-5330
Number of pages4
JournalTetrahedron Letters
Volume35
Issue number30
DOIs
StatePublished - Jul 25 1994

Keywords

  • (-)-quinic acid
  • Wittig
  • eicosanoid
  • epoxy-alcohol
  • oxiranyl-carbinol

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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