Hepoxilins B3: Synthesis of all four stereoisomers and a glutathione adduct

Yuri Y. Belosludtsev; R. Omindine Kollah; J R Falck; Jorge H. Capdevila

doi:10.1016/S0040-4039(00)73491-5

Hepoxilins B₃: Synthesis of all four stereoisomers and a glutathione adduct

Yuri Y. Belosludtsev, R. Omindine Kollah, J R Falck, Jorge H. Capdevila

Biochemistry

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Utilizing (-)-quinic acid as a differentiated bis-aldehyde chiron, both pairs of hepoxilin B₃ enantiomers and a glutathione adduct were synthesized by regiospecific functionalization of an acyclic vic-diol.

Original language	English (US)
Pages (from-to)	5327-5330
Number of pages	4
Journal	Tetrahedron Letters
Volume	35
Issue number	30
DOIs	https://doi.org/10.1016/S0040-4039(00)73491-5
State	Published - Jul 25 1994

Keywords

(-)-quinic acid
Wittig
eicosanoid
epoxy-alcohol
oxiranyl-carbinol

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/S0040-4039(00)73491-5

Cite this

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title = "Hepoxilins B3: Synthesis of all four stereoisomers and a glutathione adduct",

abstract = "Utilizing (-)-quinic acid as a differentiated bis-aldehyde chiron, both pairs of hepoxilin B3 enantiomers and a glutathione adduct were synthesized by regiospecific functionalization of an acyclic vic-diol.",

keywords = "(-)-quinic acid, Wittig, eicosanoid, epoxy-alcohol, oxiranyl-carbinol",

author = "Belosludtsev, {Yuri Y.} and Kollah, {R. Omindine} and Falck, {J R} and Capdevila, {Jorge H.}",

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T2 - Synthesis of all four stereoisomers and a glutathione adduct

AU - Belosludtsev, Yuri Y.

AU - Kollah, R. Omindine

AU - Falck, J R

AU - Capdevila, Jorge H.

PY - 1994/7/25

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N2 - Utilizing (-)-quinic acid as a differentiated bis-aldehyde chiron, both pairs of hepoxilin B3 enantiomers and a glutathione adduct were synthesized by regiospecific functionalization of an acyclic vic-diol.

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KW - Wittig

KW - eicosanoid

KW - epoxy-alcohol

KW - oxiranyl-carbinol

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