HER3 and mutant EGFR meet MET

Carlos L. Arteaga

doi:10.1038/nm0607-675

HER3 and mutant EGFR meet MET

Carlos L. Arteaga

Research output: Contribution to journal › Short survey › peer-review

66 Scopus citations

Abstract

Non-small-cell lung cancers with activating mutations in the epidermal growth factor receptor develop resistance to tyrosine kinase inhibitors by recruiting the MET receptor kinase to activate HER3 and the PI3K-Akt cell survival pathway.

Original language	English (US)
Pages (from-to)	675-677
Number of pages	3
Journal	Nature medicine
Volume	13
Issue number	6
DOIs	https://doi.org/10.1038/nm0607-675
State	Published - Jun 2007

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1038/nm0607-675

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title = "HER3 and mutant EGFR meet MET",

abstract = "Non-small-cell lung cancers with activating mutations in the epidermal growth factor receptor develop resistance to tyrosine kinase inhibitors by recruiting the MET receptor kinase to activate HER3 and the PI3K-Akt cell survival pathway.",

author = "Arteaga, {Carlos L.}",

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HER3 and mutant EGFR meet MET

Abstract

ASJC Scopus subject areas

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