60 Scopus citations

Abstract

Non-small-cell lung cancers with activating mutations in the epidermal growth factor receptor develop resistance to tyrosine kinase inhibitors by recruiting the MET receptor kinase to activate HER3 and the PI3K-Akt cell survival pathway.

Original languageEnglish (US)
Pages (from-to)675-677
Number of pages3
JournalNature medicine
Volume13
Issue number6
DOIs
StatePublished - Jun 1 2007

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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