Hereditary etiologies of hypomagnesemia

Amir Said Alizadeh Naderi, Robert F. Reilly

Research output: Contribution to journalReview articlepeer-review

32 Scopus citations

Abstract

Magnesium ions are essential to all living cells. As the second most abundant intracellular cation, magnesium has a crucial role in fundamental metabolic processes such as DNA and protein synthesis, oxidative phosphorylation, enzyme function, ion channel regulation, and neuromuscular excitability. After presenting an overview of magnesium homeostasis, we review the etiologies of hypomagnesemia, with an emphasis on hereditary causes.

Original languageEnglish (US)
Pages (from-to)80-89
Number of pages10
JournalNature Clinical Practice Nephrology
Volume4
Issue number2
DOIs
StatePublished - Feb 1 2008

Keywords

  • Bartter syndrome
  • Gitelman syndrome
  • Hypomagnesemia
  • Renal Mg handling

ASJC Scopus subject areas

  • Nephrology

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