Abstract
Magnesium ions are essential to all living cells. As the second most abundant intracellular cation, magnesium has a crucial role in fundamental metabolic processes such as DNA and protein synthesis, oxidative phosphorylation, enzyme function, ion channel regulation, and neuromuscular excitability. After presenting an overview of magnesium homeostasis, we review the etiologies of hypomagnesemia, with an emphasis on hereditary causes.
Original language | English (US) |
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Pages (from-to) | 80-89 |
Number of pages | 10 |
Journal | Nature Clinical Practice Nephrology |
Volume | 4 |
Issue number | 2 |
DOIs | |
State | Published - Feb 1 2008 |
Keywords
- Bartter syndrome
- Gitelman syndrome
- Hypomagnesemia
- Renal Mg handling
ASJC Scopus subject areas
- Nephrology