The incidence of heterotopic pregnancy is estimated to be 1 in 30,000 pregnancies with the incidence rising to approximately 1 in 100 pregnancies with the use of assisted reproductive technologies. Detection of an intrauterine pregnancy does not rule out the possibility of a simultaneous ectopic pregnancy and vice versa. When a patient is diagnosed with a heterotopic pregnancy, prompt management is preferred to prevent the need for emergent treatment of a ruptured ectopic pregnancy. Systemic methotrexate should not be used to treat the ectopic portion of a heterotopic pregnancy due to the risks to the intrauterine pregnancy. The management of an unruptured ectopic pregnancy may be accomplished by local medical management (KCl or hyperosmolar glucose, but not methotrexate) or with surgery.
- Heterotopic pregnancy
- Hyperosmolar glucose injection
- KCl injection
ASJC Scopus subject areas
- Health Professions(all)