@article{fc8d70568a7f43f18e83ee7b0ec6e56a,
title = "High-definition transcranial direct current stimulation to improve verbal retrieval deficits in chronic traumatic brain injury",
abstract = "Chronic verbal retrieval deficits have been noted in traumatic brain injury (TBI), but no U.S. Food and Drug Administration-approved interventions are available. The present study investigated whether 10 sessions of 20 min of 1 mA anodal high-definition transcranial direct current stimulation (HD-tDCS) targeting pre-supplementary motor area/dorsal anterior cingulate cortex (preSMA/dACC) compared with sham HD-tDCS would improve verbal retrieval deficits in TBI patients. Improvements in verbal retrieval processes were observed up to 8 weeks post-treatment. Thus, potential dysfunction to verbal retrieval circuitry in TBI appears amenable to remediation through electromodulation with HD tDCS to the preSMA/dACC. Although further studies clarifying mechanisms by which tDCS brought about these improvements will likely inform refinements in the application of this therapeutic technique, the findings suggest the efficacy of using HD-tDCS to target other systems vulnerable to TBI to improve functioning.",
keywords = "learning and memory, neuroplasticity, rehabilitation, traumatic brain injury",
author = "Motes, {Michael A.} and Spence, {Jeffrey S.} and Kylee Yeatman and Jones, {Penelope M.} and Morgan Lutrell and Rachel O'Hair and Scott Shakal and Delarosa, {Bambi L.} and Wing To and Sven Vanneste and Kraut, {Michael A.} and John Hart",
note = "Funding Information: The authors wish to thank the Veterans who participated in the study, and they also wish to thank the Boot Campaign for financial support and for referring participants to the study. Funding Information: Partial study funding was provided by the Boot Campaign (Assessment and Treatment of Veterans with TBI and/or PTSD, Boot Campaign; $339,963, 9/29/2016-no end date) and awarded to J. Hart, Jr. at 10% effort. Morgan Lutrell served as a Director of Development, in August of 2016, for the ReBOOT initiative for the non-profit (501c3) Boot Campaign and as interim CEO for the Boot Campaign, in January of 2017. However, he did not receive remuneration for his services in either of these roles. He was involved in the design and conceptualization or the study prior to taking on these roles, and his contributions to revisions of the manuscript came after his resignation from the Boot Campaign and after the completion of data collection for the study in 2018. Publisher Copyright: {\textcopyright} Copyright 2020, Mary Ann Liebert, Inc., publishers.",
year = "2020",
month = jan,
day = "1",
doi = "10.1089/neu.2018.6331",
language = "English (US)",
volume = "37",
pages = "170--177",
journal = "Journal of Neurotrauma",
issn = "0897-7151",
publisher = "Mary Ann Liebert Inc.",
number = "1",
}