High levels of intracellular bombesin characterize human small-cell lung carcinoma

Terry W. Moody, Candace B. Pert, Adi F. Gazdar, Desmond N. Carney, John D. Minna

Research output: Contribution to journalArticle

382 Scopus citations

Abstract

"Small cells" or "oat cells" characterize a virulent form of lung cancer and share many biochemical properties with peptide-secreting neurones. The neuropeptide bombesin is present in all small-cell lines examined, but not in other lung cancer cell lines, suggesting that bombesinergic precursor cells in lung may give rise to this disease.

Original languageEnglish (US)
Pages (from-to)1246-1248
Number of pages3
JournalScience
Volume214
Issue number4526
DOIs
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • General

Fingerprint Dive into the research topics of 'High levels of intracellular bombesin characterize human small-cell lung carcinoma'. Together they form a unique fingerprint.

  • Cite this