Highly regioselective N-trans symmetrical diprotection of cyclen

Luis M. De León-Rodríguez, Zoltan Kovacs, Ana Cristina Esqueda-Oliva, Alma Delia Miranda-Olvera

Research output: Contribution to journalArticle

47 Scopus citations


A high yielding N-trans diprotection procedure for cyclen has been developed by using succinimide carbamate derivates of Boc and Cbz and chloroformate protecting groups.

Original languageEnglish (US)
Pages (from-to)6937-6940
Number of pages4
JournalTetrahedron Letters
Issue number39
StatePublished - Sep 25 2006


ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

De León-Rodríguez, L. M., Kovacs, Z., Esqueda-Oliva, A. C., & Miranda-Olvera, A. D. (2006). Highly regioselective N-trans symmetrical diprotection of cyclen. Tetrahedron Letters, 47(39), 6937-6940. https://doi.org/10.1016/j.tetlet.2006.07.135