Resistance to EGFR kinase inhibitors appears to be invariable in the treatment of non-small cell lung cancer. Several mechanisms have been described. Here, we report the first case of histologic transformation of EGFR mutant lung adenocarcinoma without prior exposure to EGFR inhibition.
- Adenocarcinoma NSCLC
- Squamous NSCLC
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
- Cancer Research