Histologic transformation of EGFR mutant lung adenocarcinoma without exposure to EGFR inhibition

Tri Le, Joseph Sailors, Dwight H. Oliver, Melissa Mayer, Sharon Hoskin, David E. Gerber

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Resistance to EGFR kinase inhibitors appears to be invariable in the treatment of non-small cell lung cancer. Several mechanisms have been described. Here, we report the first case of histologic transformation of EGFR mutant lung adenocarcinoma without prior exposure to EGFR inhibition.

Original languageEnglish (US)
Pages (from-to)14-16
Number of pages3
JournalLung Cancer
Volume105
DOIs
Publication statusPublished - Mar 1 2017

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Keywords

  • Adenocarcinoma NSCLC
  • EGFR
  • Squamous NSCLC

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine
  • Cancer Research

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