Histological regression of giant cell tumor of bone following RANK ligand inhibition

Martin F. Dietrich, Dominick C Cavuoti, Michael J Landay, Yull E Arriaga

Research output: Contribution to journalArticle

2 Scopus citations


Lung metastases are a rare complication of giant cell tumors of bone. We herein describe an interesting case of histological regression and size reduction of lung metastases originating from a primary giant cell tumor of bone in response to the RANK ligand inhibitor denosumab.

Original languageEnglish (US)
JournalJournal of Investigative Medicine High Impact Case Reports
Issue number4
StatePublished - Jan 1 2014



  • Denosumab
  • Giant cell tumor
  • Lung metastases
  • RANK ligand

ASJC Scopus subject areas

  • Epidemiology
  • Safety, Risk, Reliability and Quality
  • Safety Research

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