Histopathological features of Kaposi's sarcoma in HIV infected individuals

Kaposi's sarcoma is the neoplasm most commonly associated with HIV infection. Since its presence in the proper clinical context is an AIDS defining event, histopathological confirmation is often required for diagnosis. It is essential that clinicians know the criteria for histopatlhological diagnosis. When the criteria outlined are followed, the diagnosis can be made with certainty in most cases. A number of conditions may simulate KS both clinically and histologically, and it is important that those who care for patients with HIV infection are aware of these.